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Part 1 of 2
CHAPTER II. ON GENERATION
I hold the following to be important and undeniable troths: That every man has a natural right both to receive and convey a knowledge of all the facts and discoveries of every art and science, excepting such only as may be secured to some particular person or persons by copyright or patent; that a physical truth in its general effect cannot be a moral evil; that no fact in physics or in morals ought to be concealed from the inquiring mind.
Some may make a misuse of knowledge, but that is their fault; and it is not right that one person should be deprived of knowledge, of spirits, of razors, or of anything else which is harmless in itself and may be useful to him, because another may misuse it.
The subject on generation is not only interesting as a branch of science, but it is so connected with the happiness of mankind that it is highly important in a practical point of view. Such, to be sure, is the custom of the age, that it is not considered a proper subject to investigate before a popular assembly, nor is it proper to attend the calls of nature in a like place; yet they must and ought to be attended to, for the good, the happiness of mankind require it; so, too, for like reason, the subject of generation ought to be investigated until it be rightly understood by all people, but at such opportunities as the good sense of every individual will easily decide to be proper. This, I presume to say, not simply upon the abstract principle that all knowledge of Nature's workings is useful, and the want of it disadvantageous, but from the known moral fact that ignorance of this process has in many instances proved the cause of a lamentable "mishap," and more especially as it is essential to the attainment of the great advantage, which it is the chief object of this work to bestow upon mankind.
People generally, as it was the case with physicians until late years, entertain a very erroneous idea of what takes place in the conception. Agreeably to this idea the "check" which I consider far preferable to any other, would not be effectual, as would be obvious to all. Consequently, entertaining this idea, people would not have due confidence in it. Hence, it is necessary to correct a long-held and widely extended error. But this I cannot expect to do by simply saying it is an error. Deeply rooted and hitherto undisputed opinions are not so easily eradicated. If I would convince any one that the steps in one of the most recondite processes of nature are not such as he has always believed, it will greatly serve my purpose to show what these steps are. I must first prepare him to be reasoned with, and then reason the matter all over with him. I must point out the facts which disprove his opinion, and show that my own is unattended with difficulties.
But what can be more obvious than that it is absolutely impossible to explain any process or function of the animal economy, so as to be understood, before the names of the organs which perform this function have been defined, that is, before the organs themselves have been described. Now it is well known to every anatomist, and indeed it may be obvious to all, that in describing any organ or system of organs, we must always begin with some external and known parts, and proceed regularly, step by step, to the internal and unknown. As in arithmetic, "everything must be understood as you go along."1
Fully to effect the objects of this work, it is, therefore, a matter of necessity that I give an anatomical description of certain parts—even external parts—which some, but imagine what I have just said, might think it useless to mention. It is not to gratify the idle curiosity of the light-minded that this book is written; it is for utility in the broad and truly philosophical sense of the term; nay, farther, it shall with the exception of here and there a little spicing*, have confined to practical utility. I shall, therefore, endeaver to treat of the subject in this chapter so as to be understood, without giving any description of the male organs of generation; though I hold it an accomplishment for one be able to speak of those organs, as diseases often put them under the necessity of doing, without being compelled use low and vulgar language. But I must briefly describe the female organs; in doing which I must, of course, speak as do other anatomists and physiologists; and whoever objects to this will discover more affectation and prudery than good sense and good will to mankind.
The adipose, or fatty matter, immediately over the share bone, forms a considerable prominence in females, which, at the age of puberty, is covered with hair, as in males. This prominence is called Mons Veneris.
The exterior orifice commences immediately below this. On each side of this orifice is a prominence continued from the mons veneris, which is largest above and gradually diminishes as it descends. These two prominences are called the Labia Externa, or external lips. Near the latter end of pregnancy they become somewhat enlarged and relaxed, so that they sustain little or no injury during parturition. Just within the upper or anterior commissure, formed by the junction of these lips, a little round oblong body is situated. The body is called the clitoris. Most of its length is bound down, as it were, pretty closely to the bone; and it is of very variable size in different females. Instances have occurred where it was so enlarged as to allow the female to have venereal commerce with others; and in Paris this fact was once made a public exhibition to the medical faculty. Women thus formed appear to partake in their general form of the male character, and are called hermaphrodites. The idea of human beings, called hermaphrodites, which could be either father or mother, is, doubtless, erroneous. The clitoris is analogous in its structure to the penis, and like it, is exquisitely sensitive, being, as it is supposed, the principal seat of pleasure. It is subject to erection or distension, like the penis, from like causes.
The skin which lines the internal surface of the external lips is folded in such manner as to form two flat bodies, the exterior edges of which are convex. They are called the nymphse. They extend downward, one on each side, from the clitoris to near the middle of the external orifice, somewhat diverging from each other. Their use is not very evident The orifice of the urethra (the canal, short in females, which leads to the bladder) is situated an inch or more farther inward than the clitoris, and is a little protuberant.
Passing by the external lips, the clitoris, the nymphse and the orifice of the urethra, we come to the membrane called the hymen. It is situated just at, or a trifle behind the orifice of the urethra. It is stretched across the passage, and were it a complete septum, it would close up the anterior extremity of that portion of the passage which is called the vagina. But the instances in which the septum or partition is complete are very rare, there being, in almost all cases, an aperture either in its center, or frequently in its anterior edge, giving the membrane the form of a crescent Through this aperture passes the menstrual fluid. Sometimes, however, this septum is complete, and the menstrual fluid is retained month after month, until appearances and symptoms much like those of pregnancy are produced, giving rise to perhaps unjust suspicions. Such cases require the simple operation of dividing the hymen. In many instances the hymen is very imperfect, insomuch that some have doubted whether it is to be found in the generality of virgins. Where it exists it is generally ruptured in the first intercourse of the sexes, and the female is said to lose her virginity. In some rare instances it is so very strong as not to be ruptured by such intercourse, and the nature of the difficulty not being understood, the husband has sued for a divorce. But everything may be put to rights by a slight surgical operation. The parts here described are among those called the external parts of generation.
The internal organs of generation consist in the female of the Vagina, the Uterus, the Ovaries and their appendages.
The Vagina is a membranous canal commencing at the hymen and extending to the uterus. It is a little curved, and extends backward and upward between the bladder, which lies before and above it, and that extreme portion of the bowels called the rectum, which lies behind it. The coat of membrane which lines the internal surface of the vagina forms a number of transverse ridges. These are to be found only in the lower or anterior half of the vagina, and they do not extend all round the vagina, but are situated on its anterior and posterior sides, while their lateral sides are smooth. I mention these ridges because a knowledge of them may lead to a more effectual use of one of the checks to be made known hereafter.
The uterus or womb is also situated between the bladder and the rectum, but above the vagina. Such is its shape that it has been compared to a pear with a long neck. There is, of course, considerable difference between the body and the neck, the first being twice as broad as the last. Each of these parts is somewhat flattened. In subjects of mature age, who have been pregnant, the whole of the uterus is about two inches and a half in length, and more than an inch and a half in breadth at the broadest part of the body. It is near an inch in thickness. The neck of the uterus is situated downward, and may be said to be inserted into the upper extremity of the vagina. It extends down into the vagina the better part of an inch. In the uterus is a cavity which approaches the triangular form, and from which a canal passes down through the neck of the uterus into the vagina. This cavity is so small that its sides are almost in contact So that the uterus is a thick, firm organ for so small a one. Comparing the cavity of the uterus to a triangle, we say the upper side or line of this triangle is transverse with respect to the body, and the other two lines pass downward and inward, so that they would form an angle below, did they not before they meet take a turn more directly downward to form the canal just mentioned. In each of the upper angles there is an orifice of such size as to admit of a hog's bristle. These little orifices are the mouths of two tubes, called the Fallopian tubes, of which more will be said presently. The canal which passes through the neck of the uterus, connecting the cavity of this organ with that of the vagina, is about a quarter of an inch in diameter. It is different from other ducts, for it seems to be a part of the cavity from which it extends, inasmuch as when the cavity of the uterus is enlarged in the progress of pregnancy, this canal is gradually converted into a part of that cavity.
The lower extremity of the neck of the uterus is irregularly convex and tumid. The orifice of the canal in it is oval, and so situated that it divides the convex surface of the lower extremity of the neck in two portions, which are called the lips of the uterus. The anterior is thicker than the posterior. The orifice itself is called os tincæ or os uteri, or in English, the mouth of the womb. When the parts are in a weak, relaxed state, the mouth or neck of the uterus is quite low, and in almost all oases it may be reached by a finger introduced into the vagina, especially by a second person, who carries the hand behind.
The Ovaries are two bodies of a flattened or oval form, one of which is situated on each side of the uterus at a little distance from it, and about as high up as where the uterus becomes narrow to form its neck. The longest diameter of the ovarium is about an inch. Each ovarium has a firm coat of membrane. In those who have not been pregnant, it contains from ten to twenty vesicles, which are little round bodies, formed of a delicate membrane, and filled with a transparent fluid. Some of these vesicles are situated so near the surface of the ovarium as to be prominent on its surface. They are of different sizes, the largest nearly a quarter of a inch in diameter.2
In those in whom conception has ever taken place, some of these vesicles are removed, and in their place a cicatrix or scar is formed which continues through life. However, the number of cicatrices does not always correspond with the number of conceptions. They often exceed it, and are sometimes found where conception has not been known to take place. The Fallopian Tubes are two canals four or five inches in length, proceeding from the upper angles of the cavity of the uterus, in a transverse direction in respect to the body. Having so proceeded for some distance they turn downward toward the ovaries. At their commencement in the uterus they are very small, but they enlarge as much as they progress. The large ends, which hang loose, terminate in open mouths, the margins of which consist of fimbriated processes, and nearly touch the ovaria.
We are now prepared to treat of conception. Yet, as menstruation is closely connected with it, and as a knowledge of many things concerning menstruation may contribute much to the well-being of females, for whom this work is at least as much designed as for males, I shall first briefly treat of this subject.
Menstruation.—When females arrive at the age of puberty they begin to have a discharge once every month, by way of the vagina, of the color of blood. This discharge is termed the menses. To have it is to menstruate. The age at which menstruation commences varies with different individuals, and also in different climates. The warmer the climate the earlier it commences and ceases. In temperate climates it generally commences at the age of fourteen or fifteen, and it ceases at forty-four, or a little later.3
Whenever it commences the girl acquires a more womanly appearance. It is a secretion of the uterus, or, in other words, the minute vessels distributed to the inner coat of uterus, select as it were, from the blood, and pour out in a gradual manner the materials of this fluid. It has one of the properties, color, of blood, but it does not coagulate, or separate into different parts like blood, and cannot properly be called blood.4
When this discharge is in all respects regular, it amounts in most females to six or eight ounces, and from two to four days' continuance. During its continuance the women is said to be unwell, or out of order. Various unpleasant feelings are liable to attend it; but when it is attended with severe pain, as it not infrequently is, it becomes a disease, and the woman is not likely to conceive until it is cured. During the existence of the "turns," or "monthlies," as they are often called, indigestible food, dancing in warm rooms, sudden exposure to cold or wet, and mental agitations, should be avoided as much as possible. The "turns" do not continue during pregnancy, nor nursing, unless nursing be continued after the "turns" recommence. Some women, it is true, are subject to a slight hemorrhage that sometimes occurs with considerable regularity during pregnancy, and which has led them to suppose they have their turns at such times; but it is not so; the discharge at such times is real blood.5
The use of the menstrual discharge seems to be to prepare the uterine system for conception. For females do not become pregnant before they commence, nor after they cease having turns; nor while they are suppressed by some disease, by cold or by nursing. Some credible women, however, have said that they become pregnant while nursing, without having had any turn since their last lying-in. It is believed that in these oases they had some discharge, colorless, perhaps, which they did not notice, but which answered the purposes of the common one. Women are not nearly so likely to conceive during the week before a monthly as during the week immediately after.6 But although the use of this secretion seems to be to prepare for conception, it is not to be inferred that the reproductive instinct ceases at the "turn of life," or when the woman ceases to menstruate. On the contrary, it is said that this passion often increases at this period, and continues in a greater or less degree to an extreme age.
Conception.—The part performed by the male in the reproduction of the species consists in exciting the organism of the female, and depositing the semen in the vagina. Before I inquire what takes place in the females I propose to speak of the semen.
This fluid, which is secreted by the testicles, may be said to possess three kinds of properties, physical, chemical, physiological. Its physical properties are known to every one—it is a thickish, nearly opaque fluid, of a peculiar odor, saltish taste, etc. As to its chemical properties, it is found by analysis to consist of 900 parts of water, 60 of animal muscilage, 10 of soda, 30 of phosphate of lime. Its physiological property is that of exciting the female genital organs in a peculiar manner.
When the semen is examined by microscope, there can be distinguished a multitude of small animalculæ, which appear to have a rounded head and a long tail. These animalculæ move with a certain degree of rapidity. They appear to avoid the light and to delight in the shade. Leeuwenhoek, if not the discoverer of the seminal animalculse, was the first who brought the fact of their existence fully before the public. With respect to their size, he remarked that ten thousand of them might exist in a space not larger than a grain of sand. They have a definite figure, and are obviously different from the animalculse found in any other fluid.7
Leeuwenhoek believed them to be the beginnings of future animals—that they are of different sexes, upon which depends the future sex of the foetus. Be this as it may, it appears to be admitted on all hands that the animalculæ are present in the semen of the various species of male animals, and that they cannot be detected when either from age or disease the animals are rendered sterile. "Hence," says Bostock, "we can scarcely refuse our assent to the position that these animalculæ are in some way or other instrumental to the production of the foetus." The secretion of the semen commences at the age of puberty. Before this period the testicles secrete a viscid, transparent fluid, which has never been analyzed, but which is doubtless essentially different from semen. The revolution which the whole economy undergoes at this period, such as the tone of the voice, and development of hairs, the beard, the increase of the muscles and bones, etc., is intimately connected with the testicles and the secretion of this fluid.8 "Eunuchs preserve the same form as in childhood; their voice is effeminate, they have no beard, their disposition is timid; and finally their physical and moral character very nearly resembles that of females. Nevertheless, many of them take delight in venereal intercourse, and give themselves up with ardor to a connection which must always prove unfruitful."9
The part performed by the female in the reproduction of the species is far more complicated than that performed by the male. It consists, in the first instance, in providing a substance which, in connection with the male secretion, is to constitute the foetus; in furnishing a suitable situation in which the foetus may be developed; in affording due nourishment for its growth; in bringing it forth, and afterward furnishing it with food especially adapted to the digestive organs of the young animal. Some parts of this process are not well understood, and such variety of hypotheses have been proposed to explain them that Drelincourt, who lived in the latter part of the seventeenth century, is said to have collected two hundred and sixty hypotheses of generation.
It ought to be known that women have conceived when the semen was merely applied to the parts anterior to the hymen, as the internal surface of the external lips, the nymphæ, etc. This is proved by the fact that several cases of pregnancy have occurred when the hymen was entire. The fact need not surprise us, for, agreeable to the theory of absorption, we have to account for it only to suppose that some of the absorbent vessels are situated anterior to the hymen—a supposition by no means unreasonable.
There are two peculiarities of the human species respecting conception which I will notice. First, unlike other animals they are liable, and for what has been proved to the contrary, equally liable—to conceive at all seasons of the year. Second, a woman rarely, if ever, conceives until after having several sexual connections; nor does one connection in fifty cause conception in the matrimonial state, where the husband and wife live together uninterruptedly. Public women rarely conceive, owing probably to a weakened state of the genital system, induced by too frequent and promiscuous intercourse.
It is universally agreed, that some time after a fruitful connection, a vesicle (two in case of twins) of one or the other ovary becomes so enlarged that it bursts forth from the ovary and takes the name of ovum, which is taken up, or rather received, as it bursts forth, by the fimbriated extremity of the Fallopian tube, and is then conducted along the tube into the uterus, to the inner surface of which it attaches itself.10
Here it becomes developed into a full grown foetus, and is brought forth about forty-two weeks from the time of conception by a process termed parturition. But one grand question is, how the semen operates itself, or any part thereof reaches the ovary, and if so, in what way it is conveyed to them. It was long the opinion that the semen was ejected into the uterus in the act of coition, and that it afterward, by some unknown means, found its way into and along the Fallopian tubes to the ovary. But there are several facts which weigh heavily against this opinion, and some that entirely forbid it. In the first place, there are several well attested instances in which impregnation took place while the hymen remained entire, where the vagina terminated in the rectum, where it was so contracted by a cicatrix as not to admit the penis. In all these cases the semen could not have been lodged anywhere near the mouth of the uterus, much less ejected into it. Secondly, it has followed a connection where from some defect in the male organs, as the urethra terminating some inches behind the end of the penis, and it is clear that the semen could not have been injected into the uterus, nor even near its mouth. Third, the neck of the unimpregnated uterus is so narrow as merely to admit a probe, and is filled with a thick tenacious fluid, which seemingly could not be forced away by any force which the male organ possesses of ejecting the semen, even if the mouth of the male urethra were in opposition with that of the uterus. But fourth, the mouth of the uterus is by no means fixed. By various causes it is made to assume various situations, and probably the mouth of the urethra rarely comes in contact with it.
Fifth. "The tenacity of the male semen is such as renders its passage through the small aperture in the neck of the uterus impossible, even by a power of force much superior to that which we may rationally suppose to reside in the male organs of generation."
Sixth. "Harvey and DeGraaf dissected animals at almost every period after coition for the express purpose of discovering the semen, but were never able to detect the smallest vestige of it in the uterus in any one instance."11
Aware of the insurmountable objection to this view of the manner in which the semen reaches the ovary, it has been supposed by some physiologists that the semen is absorbed from the vagina into the great circulating system, where it is mixed, of course, with the blood, and goes the whole round of the circulation subject to the influence of those causes which produce great changes in the latter fluid.
To this hypothesis it may be objected, that while there is no direct evidence in support of it, it is exceedingly unreasonable, inasmuch as we can scarcely believe that the semen can go the whole round of circulation, and then find its way to the ovary in such a pure unaltered state as the experiments of Spallanzani prove it must be in, that it may impregnate.
A third set of theorists have maintained that an imperceptible something, which they have called aura seminalis, passes from the semen lodged in the vagina to the ovary, and excites those actions which are essential to the development of an ovum. Others, again, have told us that it is all done by sympathy. That neither the semen nor any volatile part of it finds its way to the ovary; but that the semen excites the parts with which it is in contact in a peculiar manner, and by the law of animal economy, termed sympathy, or consent of parts, a peculiar action commences in the ovary, by which an ovum is developed.
To both these conjectures it may be objected that they have no other foundation but the supposed necessity of adopting them, to account for the effect of impregnation; and, further, they "make no provision for the formation of mules; for the peculiarities of, and likeness to, parents, and for the propagation of predisposition to disease, from parent to child; for the production of mulattoes," etc.
A fifth, and to me far more satisfactory view of the subject than any other, is that advanced by our distinguished countryman, Dr. Dewees, of Philadelphia. It appears to harmonize with all known facts relating to the conception and something from analogy may also be drawn in its favor. It is this, that there is a set of absorbent vessels, leading directly from the inner surface of the labia externa and the vagina, to the ovaries, the whole office of which vessels is to absorb the semen and convey it to the ovaries.12 I do not know that these vessels have yet been fully discovered, but in a note on the sixteenth page of his "Essays on Various Subjects," the doctor says: "The existence of these vessels is now rendered almost certain, as Dr. Gartner, of Copenhagen, has discovered a duct leading from the ovary to the vagina."
Another question of considerable moment relating to generation is from which parent are the first rudiments of the foetus derived.
The earliest hypothesis with which we are acquainted, and which has received the support of some of the most eminent of the moderns, ascribes the original formation of the foetus to the combination of particles of matter derived from each of the parents. This hypothesis naturally presents itself to the mind as the obvious method of explaining the necessity for the cooperation of the two sexes, and the resemblance in external form, and even in mind and character, which the offspring often bears to the male parent. "The principal objections," says Bostock, "to his hypothesis, independent of the want of any direct proof of a female seminal fluid, are of two descriptions, those which depend upon the supposed impossibility of unorganized matter forming an organized being, and those which are derived from observations and experiments of Haller and Spallanzani, which they brought forward in support of their theory of pre-existent germs."
In relation to these objections I remark, first those whose experience has been with hale females, I suspect, can have no doubt but that the female organism increases like that of the male, until an emission of fluid of some kind or other takes place. But whether this secretion may properly be called semen, whether any part of it unites with the male semen in forming the rudiments of the foetus, is another question. For my part I am inclined to the opinion that it does not.13 I rather regard it as the result of exalted excitation, analogous to the increased secretion of other organs from increased stimulation; and if it may be for any object or use, as it probably is, it is that of affording nature a means of relieving herself; or, in other words, of quieting the venereal passion. If this passion, being once roused, could not by some means or other be calmed, it would command by far too great a portion of our thoughts, and with many constitutions the individuals, whether male or female, could not conduct themselves with due decorum. One fact which leads me to think that the female secretion in the act of coition is not essential to impregnation is, that many females have conceived, if their unbiased testimony may be relied on, when they experienced no pleasure. In these cases it is more than probable that there was no orgasm, nor any secretion or emission of fluid on the part of the female.
As to the objection of the supposed impossibility of unorganized matter forming an organized being, I do not believe such a thing takes place, even if we admit that "the original formation of the foetus is a combination of particles of matter derived from each of the parents." What do, or rather what ought we to mean by organized matter? Not, surely, that it exhibits some obvious physical structure, unlike what is to be found in inorganic matter, but that it exhibits phenomena, and of course may be said to possess properties unlike any kind of inorganic matter. Matter unites with matter in three ways, mechanically, chemically and organically, and each mode of union gives rise to properties peculiar to itself. When matter unites organically, the substance or being so formed exhibits some phenomena essentially different from what inorganic bodies exhibit. It is on this account that we ascribe to organic bodies certain properties, which we call physiological properties, such as contractility, sensibility, life, etc. When, from any cause, these bodies have undergone such a change that they no longer exhibit the phenomena peculiar to them, they are said to have lost these properties, and to be dead. A substance need not possess all the physiological properties of an animal of the higher orders to entitle it to the name of an organized or living substance, nor need it possess the physical property of solidity. The blood, as well as many of the secretions, does several things, exhibits several phenomena, which no mechanical or mere chemical combinations of matter do exhibit. We must therefore ascribe to it certain physiological properties, and regard it as an organized, a living fluid, as was contended by the celebrated John Hunter. So with respect to the semen, it certainly possesses physiological properties, one in particular peculiar to itself, namely, the property of impregnating the female; and upon no sound principle can it be regarded in any other light than as an organized, and of course a living fluid. And if the female secretion or any part of it unite with the male secretion in the formation of the rudiments or the foetus in a different manner than any other substance would, then it certainly has the property of doing so, whether we give this property a name or not; and a regard to the soundest principles of physiology compels us to class this property with the physiological or vital, and of course to regard this secretion as an organized and living fluid So, then, unorganized matter does not form an organized being, admitting the hypothesis before us as correct.
That organized being should give rise to other organized beings under favorable circumstances as to nourishment, warmth, etc., is no more wonderful than that fire should give rise to fire when air and fuel are present. To be sure, there are some minute steps in the processes which are not fully known to us; still, if they ever should be known, we should unquestionably see that there is a natural cause for every one of them; and that they are all consonant with certain laws of the animal economy. We should see no necessity of attempting to explain the process of generation by bringing to our aid, or rather to the darkening of the subject, any imaginary principle, as the visus formaticus of Blumenbach.
As to the "observations and experiments of Haller and Spallanzani," I think, with Dr. Bostock, that they weigh but little, if any, against the theory before us. I shall not be at the labor of bringing them forward and showing their futility as objections to this theory, for I am far from insisting on the correctness of it; that is, I do not insist that any part of the female secretion, during coition, unites with the male semen in the formation of the rudiments of the foetus.
The second hypothesis or theory, I shall notice, as to the rudiments of the foetus, is that of Leeuwenhoek, who regarded the seminal animalculse of the male semen as the proper rudiments of the foetus, and thought that the office of the female is to afford them a suitable receptacle where they may be supported and nourished until they are able to exist by the exercise of their own functions. This is essentially the view of the subject which I intend to give more particularly presently.
I know of no serious objections to this hypothesis, nothing but the "extreme improbability," as its opponents say, "that these animalculæ should be the rudiments of being so totally dissimilar to them." But I wish to know if there is more difference between a foetus and a seminal animalcule than there is between a foetus and a few material particles in some other form than that of such animalcule?
The third hypothesis, or that of pre-existing germs, proceeded upon a precisely opposite view of the subject to that of Leeuwenhoek, namely, that the foetus is properly the production of the female; that it exists previous to the sexual congress, with all its organs, in some parts of the uterine system; and that it receives no proper addition from the male, but that the seminal fluid acts merely by exciting the powers of the foetus, or endowing it with vitality.
It is not known who first proposed this hypothesis; but strange as it may appear, it has had the support of such names as Bonnet, Haller and Spallanzani, and met with a favorable reception in the middle of the last century. Agreeable to this hypothesis, our common mother, Eve, contained a number of homuncules (little men) one within another, like a nest of boxes, and all within her ovaries, equal to all the number of births that have ever been, or ever will be, not to reckon abortions. Were I to bring forward all the facts and arguments that have been advanced in support of this idea, it seems to me I should fail to convince sound minds of its correctness; as to arguments against it, they surely seem uncalled for. Having now presented several hypotheses of generation, some as to the manner in which the semen reaches or influences the ovary, and others as to the rudiments of the foetus, I shall now bring together those views which, upon the whole, appear to me the most satisfactory.